Publications

Lovell, J.F.; Jin, C.S.; Huynh, E.; MacDonald, T.D.; Cao, W. & Zheng G.
Enzymatic Regioselection for the Synthesis and Biodegradation of Porphysome Nanovesicles.
Angewandte Chemie, Int. Ed., 2012.
Jin, H.; Lovell, J.F.; Chen, J.; Lin, Q.; Ding, L.; Ng, K.; Pandey, R.; Manoharan, M.; Zhang, Z. & Zheng G.
Mechanistic insights into LDL nanoparticle-mediated siRNA delivery.
Bioconjugate Chemistry, 2011.
Mawn T.M.; Popov A.V.; Beardsley N.J.; Milkevitch M.; Stefflova K.; Zheng G. & Delikatny EJ.
In vivo Detection of Phospholipase C by Enzyme-Activated Near-infrared Probes.
Bioconjugate Chemistry, 2011.
Lovell, J.F.; Chan, M.W.; Qi, Q.; Chen, J. & Zheng, G.
Porphyrin FRET Acceptors for Apoptosis Induction and Monitoring.
Journal of the American Chemical Society, 2011.
Shi, J.; Liu, T.W.; Chen, J.; Green, D.; Jaffray, D.; Wilson, B.C.;Wang, F. & Zheng, G.
Transforming a Targeted Porphyrin Theranostic Agent into a PET Imaging Probe for Cancer.
Theranostics, 2011.
Jin, C.S. & Zheng, G.
Liposomal Nanostructures for Photosensitizer Delivery.
Lasers in Surgery and Medicine, 2011.
Liu, T.W.; Chen, J.; Burgess, L.; Cao, W.; Shi, J.; Wilson, B.C. & Zheng, G.
Multimodal Bacteriochlorophyll Theranostic Agent.
Theranostics, 2011.
Lovell, J.F.; Roxin, A.; Ng, K.K.; Qi, Q.; McMullen, J.D.; DaCosta, R.S. & Zheng, G.
Porphyrin-Crosslinked-Hydrogel for Fluorescence-Guided Monitoring and Surgical Resection.
Biomacromolecules, 2011.
Liu, T.W.; Akens, M.K; Chen, J.; Wise-Milestone, L.; Wilson, B.C. & Zheng, G.
Imaging of Specific Activation of Photodynamic Molecular Beacons in Breast Cancer Vertebral Metastases.
Bioconjugate Chemistry, 2011.
Yang, M.; Chen, J.;, Cao, W.; Ding, L.; Ng, K.K.; Jin, H.; Zhang, Z. & Zheng, G.
Attenuation of Nontargeted Cell-Kill Using a High-Density Lipoprotein-Mimicking Peptide-Phospholipid Nanoscaffold.
Nanomedicine, 2011.
Ng, K.K.; Lovell, J.F. & Zheng, G.
Lipoprotein-Inspired Nanoparticles for Cancer Theranostics.
Accounts of Chemical Research, 2011.
Marotta, D.E.; Cao, W.;, Wileyto, E.P.; Li, H.; Corbin, I.; Rickter, E.; Glickson, J.D.; Chance, B.; Zheng, G. & Busch, T.M.
Evaluation of Bacteriochlorophyll-Reconstituted Low-Density Lipoprotein Nanoparticles for photodynamic Therapy Efficacy In Vivo.
Nanomedicine, 2011, 6, 475-487.
Lovell, J.F.; Jin, C.S.; Huynh, E.; Jin, H.; Kim, C.; Rubinstein, J.L.; Chan, W.C.W.; Cao, W.; Wang, L.V. & Zheng, G.
Porphysome Nanovesicles Generated by Porphyrin Bilayers for use as Multimodal Biophotonic Contrast Agents.
Nature Materials, 2011, 20, 324-332.
Jin, H.; Lovell, J.F.; Chen, J.; Ng, K.K.; Ding, L.; Zhang, Z. & Zheng, G.
Cytosolic Delivery of LDL Nanoparticle Cargo Using Photochemical Internalization.
Photochem. Photobiol. Sci., 2011, 10, 810-816.
Yang, M.; Jin, H.; Chen, J.; Ding, L.; Ng., K.K.; Lin, Q.; Lovell, J.F.; Zhang, Z. & Zheng, G.
Efficient Cytosolic Delivery of siRNA Using HDL-Mimicking Nanoparticles.
Small, 2011, 7, 568-573.
Tam, N.C.; Scott, B.M.T.; Voicu, D.; Wilson, B.C. & Zheng, G.
Facile Synthesis of Raman Active Phospholipid Gold Nanoparticles.
Bioconjugate Chemistry, 2010, 21, 2178-2182.
Jin, H.; Lovell, J.F.; Chen, J.; Ng, K.K.; Cao, W.; Ding, L.; Zhang, Z. & Zheng, G.
Investigating the Specific Uptake of EGF-Conjugated Nanoparticles in Lung Cancer Cells Using Fluorescence Imaging.
Cancer Nanotechnology, 2010, 1, 71-78.
Lovell, J.F.; Jin, H.; Ng, K.K. & Zheng, G.
Programmed Nanoparticle Aggregation Using Molecular Beacons.
Angewandte Chemie, Int. Ed., 2010, 49, 7917-7919.
Hill, M.L.; Corbin, I.R.; Levitin, R.B.; Cao, W.; Mainprize, J.G.; Yaffe, M.J. & Zheng, G.
In vitro Assessment of Poly-iodinated Triglyceride Reconstituted Low-Density Lipoprotein: Initial Steps Toward CT Molecular Imaging.
Academic Radiology, 2010, 17, 1359-1365.
Lovell, J.F.; Chen, J.; Huynh, E.; Jarvi, M.T.; Wilson, B.C. & Zheng, G.
Facile Synthesis of Advanced Photodynamic Molecular Beacon Architectures.
Bioconjugate Chem., 2010, 21, 1023-1025
Liu, T.W.B.; Chen, J. & Zheng, G.
Peptide-based Molecular Beacons for Cancer Imaging and Therapy.
Amino Acids, 2010
Lovell, J.F.; Liu, T.W.B.; Chen, J. & Zheng, G.
Activatable Photosensitizers for Imaging and Therapy.
Chemical Reviews, 2010, 110, 2839-2857
Zhang, Z.; Chen, J.; Ding, L.; Jin, H.; Lovell, J.F.; Corbin, I.R.; Cao, W.; Lo, P.; Yang, M.; Tsao, M.; Luo, Q. & Zheng, G.
HDL-Mimicking Peptide-Lipid Nanoparticles with Improved Tumor Targeting.
Small, 2010, 6, 430-437
Zhang, Z.; Cao, W.; Jin, H.; Lovell, J.F.; Yang, M.; Ding, L.; Chen, J.; Corbin, I.; Luo, Q. & Zheng, G.
Biomimetic Nanocarrier for Direct Cytosolic Drug Delivery.
Angewandte Chemie, Int. Ed., 2009, 48, 9171-9175
Cao, W.; Ng, K.K.; Corbin, I.; Zhang, Z.; Ding, L.; Chen, J. & Zheng, G.
Synthesis and Evaluation of a Stable Bacteriochlorophyll-Analog and Its Incorporation into High-Density Lipoprotein Nanoparticles for Tumor Imaging.
Bioconjugate Chem., 2009, 20, 2023-2031
Chen, J.; Liu, T.W.B.; Wilson, B.C. & Zheng, G.
"Zipper" Molecular Beacons: A Generalized Strategy to Optimize the Performance of Activatable Protease Probes.
Bioconjugate Chem., 2009, 20, 1836-1842
Lovell, J.F.; Chen, J.; Jarvi, M.T.; Cao, W.; Allen, A.D.; Liu, Y.; Tidwell, T.T.; Wilson, B.C. & Zheng, G.
FRET Quenching of Photosensitizer Singlet Oxygen Generation
J. Phys. Chem. B, 2009, 113, 3203-3211
Lo, P.; Chen, J; Stefflova, K.; Warren, M.S.; Navab, R.; Bandarchi, B.; Mullins, S.; Tsao, M. Cheng, J.D. & Zheng, G.
Photodynamic Molecular Beacon Triggered by Fibroblast Activation Protein on Cancer-Associated Fibroblasts for Diagnosis and Treatment of Epithelial Cancers
J. Med. Chem., 2009, 52, 358-368
Lovell, J.F.& Zheng, G.
Activatable smart probes for molecular optical imaging and therapy
J. Innov. Opt. Health. Sci., 2008, 1, 45-61       pdf
Chen, J.; Lovell, J.F.; Lo, P.; Stefflova, K.; Niedre, M.; Wilson, B.C. & Zheng, G.
A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production.
Photochem. Photobiol. Sci., 2008, 7, 775-781
Chen, J.; Jarvi, M.; Lo, P.; Stefflova, K.; Wilson, B.C. & Zheng, G.
Using the singlet oxygen scavenging property of carotenoid in photodynamic molecular beacons to minimize photodamage to non-targeted cells.
Photochem. Photobiol. Sci., 2007, 6, 1311-1317
Zheng, G.; Chen, J.; Stefflova, K.; Jarvi, M.; Li, H. & Wilson, B.C.
Photodynamic molecular beacon as an activatable photosensitizer based on protease-controlled singlet oxygen quenching and activation
Proc. Natl. Acad. Sci. U. S. A., 2007, 104, 8989-8994       pdf
Chen, J.; Corbin, I.R.; Li, H.; Cao, W.; Glickson, J.D. & Zheng, G.
Ligand conjugated low-density lipoprotein nanoparticles for enhanced optical cancer imaging in vivo
J. Am. Chem. Soc., 2007, 129, 5798-5799
Stefflova, K.; Chen, J. & Zheng, G.
Killer beacons for combined cancer imaging and therapy
Curr. Med. Chem., 2007, 14, 2110-2125
Stefflova, K.; Chen, J. & Zheng, G.
Using molecular beacons for cancer imaging and treatment
Front. Biosci., 2007, 12, 4709-4721
Stefflova, K.; Li, H.; Chen, J. & Zheng, G.
Peptide-based pharmacomodulation of a cancer-targeted optical imaging and photodynamic therapy agent
Bioconjug. Chem., 2007, 18, 379-388
Corbin, I.R. & Zheng, G.
Mimicking nature's nanocarrier: synthetic low-density lipoprotein-like nanoparticles for cancer-drug delivery
Nanomed., 2007, 2, 375-380
Corbin, I. R.; Li, H.; Chen, J.; Lund-Katz, S.; Zhou, R.; Glickson, J. D. & Zheng, G.
Low-density lipoprotein nanoparticles as magnetic resonance imaging contrast agents
Neoplasia, 2006, 8, 488-498       pdf
Stefflova, K.; Chen, J.; Li, H. & Zheng, G.
Targeted photodynamic therapy agent with a built-in apoptosis sensor for in vivo near-infrared imaging of tumor apoptosis triggered by its photosensitization in situ
Mol. Imaging, 2006, 5, 520-532
Stefflova, K.; Chen, J.; Marotta, D.; Li, H. & Zheng, G.
Photodynamic therapy agent with a built-in apoptosis sensor for evaluating its own therapeutic outcome in situ
J. Med. Chem., 2006, 49, 3850-3856
Li, H.; Marotta, D.E.; Kim, S.; Busch, T. M.; Wileyto, E.P. & Zheng, G.
High payload delivery of optical imaging and photodynamic therapy agents to tumors using phthalocyanine-reconstituted low-density lipoprotein nanoparticles
J. Biomed. Opt., 2005, 10, 41203
Zheng, G.; Chen, J.; Li, H. & Glickson, J. D.
Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents
Proc. Natl. Acad. Sci. U. S. A., 2005, 102, 17757-17762
Wu, S.P.; Lee, I.; Ghoroghchian, P.P.; Frail, P.R.; Zheng, G.; Glickson, J.D. & Therien, M.J.
Near-infrared optical imaging of B16 melanoma cells via low-density lipoprotein-mediated uptake and delivery of high emission dipole strength tris[(porphinato)zinc(II)] fluorophores
Bioconjug. Chem., 2005, 16, 542-550
Zhang, Z.; Li, H.; Liu, Q.; Zhou, L.; Zhang, M.; Luo, Q.; Glickson, J.; Chance, B. & Zheng, G.
Metabolic imaging of tumors using intrinsic and extrinsic fluorescent markers
Biosens. Bioelectron., 2004, 20, 643-650
Li, H.; Zhang, Z.; Blessington, D.; Nelson, D. S.; Zhou, R.; Lund-Katz, S.; Chance, B.; Glickson, J. D. & Zheng, G.
Carbocyanine labeled LDL for optical imaging of tumors
Acad. Radiol., 2004, 11, 669-677
Zhang, Z.; Blessington, D.; Li, H.; Busch, T.M.; Glickson, J.; Luo, Q.; Chance, B. & Zheng, G.
Redox ratio of mitochondria as an indicator for the response of photodynamic therapy
J. Biomed. Opt., 2004, 9, 772-778
Chen, J.; Stefflova, K.; Niedre, M. J.; Wilson, B.C.; Chance, B.; Glickson, J.D. & Zheng, G.
Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation
J. Am. Chem. Soc., 2004, 126, 11450-11451