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Dr. Niall D. Ferguson

Biographical Sketch
University Appointments
Hospital Appointments
Clinical Activities
Educational Activities
Current Activities
Research Interests
Selected Publications

Biographical Sketch


Dr. Niall Ferguson is Head of Critical Care Medicine at the University Health Network and Mount Sinai Hospital, and Associate Professor of Medicine and Physiology at the University of Toronto.  He is a Scientist in the Toronto Western Research Institute, and the Critical Care Lead for the Toronto-Central Local Health Integration Network.  He received his M.D. with honours from the University of Toronto in 1995, and went on to complete post-graduate training in Internal Medicine, Respirology, and Critical Care Medicine.  Dr. Ferguson completed a Master’s degree in Clinical Epidemiology and Health Care Research at the University of Toronto in 2002, and subsequently undertook a Post-doctoral Fellowship in Madrid, Spain.  He receives research funding from local, provincial, and national agencies, including the Canadian Institutes of Health Research.  Dr. Ferguson’s research, which is published in high-impact journals including the New England Journal of Medicine, JAMA, and the American Journal of Respiratory & Critical Care Medicine focuses on: (1) mechanical ventilation (epidemiology; weaning and liberation; extubation and tracheostomy); (2) acute respiratory distress syndrome (definitions; ventilatory management; trial design); and (3) novel modes of mechanical ventilation.  Dr. Ferguson is also the Scientific Programme Chair for Critical Care Canada Forum, Canada’s premier critical care conference.  He is a frequent invited-speaker at national and international meetings, having given over 200 such talks.

Dr. Niall Ferguson is Head of Critical Care Medicine at the University Health Network and Mount Sinai Hospital, and Associate Professor of Medicine and Physiology at the University of Toronto.  He is a Scientist in the Toronto Western Research Institute, and the Critical Care Lead for the Toronto-Central Local Health Integration Network.  Dr. Ferguson’s research, which is supported by local, provincial, and national granting agencies, focuses on: (1) mechanical ventilation (epidemiology; weaning and liberation; extubation and tracheostomy); (2) acute respiratory distress syndrome (definitions; ventilatory management; trial design); and (3) novel modes of mechanical ventilation.  Dr. Ferguson is also the Scientific Programme Chair for Critical Care Canada Forum, Canada’s premier critical care conference.

University Appointments

Assistant Professor of Medicine

Hospital Appointments

Staff Physician, University Health Network
Director of Clinical Research, Critical Care Medicine, University Health Network

Clinical Activities

Medical-Surgical-Neurosurgical ICU attending ~ 1 week per month (Toronto Western)
Respirology in-patient consult service attending ~ 8 weeks per year (Toronto Western)

Educational Activities

Foundations of Medical Practice PBL Tutor
Department of Medicine Noon Rounds ~ 1 per 2 months
ICU Resident Seminars 3-4 per ICU attending week
Respirology Resident Seminars 1-2 per Respirology attending week

Current Local, Provincial, National and International Activities

Local
Critical Care Medicine Research Advisory Committee (Secretary), Interdepartmental Division of Critical Care Medicine, University of Toronto
Executive Committee (Research Committee representative), Interdepartmental Division of Critical Care Medicine, University of Toronto
Resident Interview & Selection Committee, Interdepartmental Division of Critical Care Medicine, University of Toronto
MSICU Multidisciplinary Quality Committee, Toronto Western Hospital, University Health Network

National
Scientific Advisor, Toronto Critical Care Medicine Symposium 2004

International
Reviewer for the following journals: American Journal of Respiratory & Critical Care Medicine, Critical Care Medicine, Intensive Care Medicine, Critical Care, and the Journal of Critical Care Editorial Board member of Medicina Intensiva
Reviewer for Practical Reviews in Critical Care Medicine (jointly produced by the Johns Hopkins University School of Medicine and Oakstone Medical Publishing)

Research Interests

Mechanical ventilation - epidemiology, weaning, extubation failure
High-frequency oscillatory ventilation
Acute Respiratory Distress Syndrome - treatment and definitions
Weaning and extubation decisions in brain-injured patients

Current Grant Support

The Design and Planning of a RCT of High-Frequency Oscillation vs. Conventional Mechanical Ventilation in Patients with Severe ARDS
Principal Investigator: ND Ferguson
Agency: Canadian Institutes of Health Research, RCT Mentoring Program
Funds Granted: $160,000, 2006-2008

Improving Best Practice Utilization in Critical Care
Principal Investigator: C Hayes
Co-investigators: ND Ferguson, SE Lapinsky, SF Reynolds, DC Scales
Agency: Chair of Medicine - Hospital Partners Safety/Quality Award, University of Toronto
Funds Granted: $20,000, 2006

Patient Evaluations Ranking Methods for Inclusion in Trials (PERMIT) pilot study
Co-Principal Investigators: DC Scales, ND Ferguson
Co-investigators: JO Friedrich, OM Smith, KA Barrett, NM Lazar
Agency: Canadian Intensive Care Foundation
Funds Granted: $20,000, 2005-2006

Patient Evaluations Ranking Methods for Inclusion in Trials (PERMIT) pilot study
Co-Principal Investigators: ND Ferguson, DC Scales
Co-investigators: JO Friedrich, NM Lazar, DJ Cook
Agency: The Physicians' Services Incorporated Foundation
Funds Granted: $76,000, 2005-2006

PROTECT: PROphylaxis of ThromboEmbolism in Critical Care Trial
Principal Investigator: DJ Cook
Co-investigators: PC Hébert, MO Meade, MA Crowther, GH Guyatt, DR Anderson, SM Bates, J Muscedere, M Albert, Y Skrobik, SP Keenan, G. Paglierello, CG Rabbat, WH Geerts, S Walter, RA Fowler, PM Dodek, ND Ferguson, JC Marshall, GM Rocker, S Mehta, DR Chittock, JT Granton, TE Warkentin, S Langevin, CM Martin, MD Sharpe, MS Dial, G Poirier, AR Moody, D Schiff, A Frietag, SR Kahn, DJ Kutsogiannis, JF Cade, C Doig, JA Myburgh, SR Finfer, DJ Cooper
Agency: Canadian Institutes of Health Research
Funds Granted: $4,880,347, 2005-2008

Quality-Adjusted Life Years as an Outcome in Critical Care
Principal Investigator: ND Ferguson
Co-investigators: DC Scales, MO Meade, TE Stewart, MS Herridge, JC Marshall Agency: Ontario Thoracic Society - Block Term Grant
Funds Granted: $2,000, 2005-2006

Neurological ICU Extubation strategy Utilization and Reintubation Outcomes NEURO)observational pilot study
Principal Investigator: ND Ferguson
Co-investigators: NJ Adhikari, RA Fowler, DC Scales
Agency: University of Toronto Connaught New Staff Matching Grant
Funds Granted: $20,000, 2005-2006

Selected Recent Publications

Click here for search results from PubMed

Chapters and Monographs

Tsang JLY, Ferguson ND. Liberation from Mechanical Ventilation in Acutely Brain-Injured Patients. In: Vincent JL (Ed) 2006 Yearbook of Intensive Care and Emergency Medicine. Springer Verlag, Berlin, pp 237-243, 2006. Role: Senior responsible author; supervised J Tsang, postgraduate medical trainee

Singh JM, Ferguson ND, Stewart TE. Rationale for High Frequency Oscillatory Ventilation in Acute Lung Injury. In: Dreyfuss D (Ed) Ventilator-Induced Lung Injur. Marcel Dekker, New York, pp 697-710, 2006. Role: Co-principal author

Ferguson ND, Slutsky AS. Ventilation Mechanical: Non-invasive Ventilation. In: Laurent GJ and Shapiro SD (Eds) Encyclopedia of Respiratory Medicine. Elsevier, Oxford, pp 455-459, 2006. Role: Principal author