Dr. Lianne Singer

Biographical Sketch

Dr. Singer completed medical school, Internal Medicine and Respirology training at the University of Toronto. She went on to do a Lung and Heart-Lung Transplantation Fellowship at Stanford University, and advanced training in clinical research at the University of California, San Francisco. She has been on faculty since 2001.

University Appointments

Assistant Professor , Department of Medicine, University of Toronto
Associate Member, Institute of Medical Science, University of Toronto

Hospital Appointments

Member, Toronto General Research Institute
Staff Physician, University Health Network, Toronto
Staff Physician, Mount Sinai Hospital, Toronto

Clinical Activities

Medical Director, Toronto Lung Transplant Program
Clinical Trials Director, Multi-Organ Transplant Program, University Health Network, Toronto

Educational Activities

Executive Committee, CIHR Training Program in Regenerative Medicine
Director of Visiting Lecturer Series, CIHR Training Program in Regenerative Medicine

Current Local, Provincial, National and International Activities

Women's Issues Committee, Department of Medicine, University Health Network / Mount Sinai Hospital
National Grant Review Committee, Canadian Lung Association
Standards Committee, Canadian Thoracic Society
Chair, Transplant / Immunology NetWork Steering Committee, American College of Chest Physicians
Committee for revision of the International Guidelines for the Selection of Lung Transplant Candidates, International Society of Heart and Lung Transplantation

Research Interests

My research interests arise directly from my clinical focus in lung transplantation. Research subjects include health-related quality of life assessment in advanced lung disease and lung transplantation, decision analysis modeling of lung transplant outcomes to inform clinical decision making and organ allocation policy, and the impact of post-transplant weight gain on clinical and functional outcomes.

My methodologic interests include health utility assessment and validation, internet-based health-related quality of life assessment, and decision analysis.

Current Grant Support

Canadian Institutes of Health Research
2006-09
Health-related quality of life in advanced lung disease and lung transplantation.
Investigators: LG Singer (Principal Investigator), MD Krahn, DE Tullis, JT Granton, TK Waddell, M Faughnan, T Marras
Annual amount: $80,343

Physicians Services Incorporated
2004-2005
Health-related quality of life in advanced lung disease and lung transplantation.
Investigators: LG Singer (Principal Investigator), MD Krahn, DE Tullis, JT Granton, TK Waddell
$68,500

Ontario Thoracic Society Block Term Grant
2004-2005
Prevalence of sleep-disordered breathing in lung transplant recipients: a pilot study.
Investigators: LG Singer (Principal Investigator)
$9900

Canadian Institutes of Health Research
2002 - 2007
Training Program in Regenerative Medicine
Investigators: GA Levy (Principal Investigator), Co-Investigators: LG Singer, A Humar, MJH Ratcliffe, AK Stewart, G Downey, J Gauldie, M Rudnicki, A Daar, L Cicutto, MV Sefton
$1,500,000

Canadian Cystic Fibrosis Foundation
2004-2005
Lung Transplant Program Incentive Grant
Co-Applicants: LG Singer, S Keshavjee
$56,083

Selected Recent Publications

Click here for search results from PubMed

Singer LG, Gould MK, Tomlinson G, Theodore J. Determinants of health utility in lung transplant recipients. American Journal of Transplantation (in press)

Pakhale SS, Hadjiliadis D, Palmer SM, Gutierrez C, Chamberlain D, Davis RD, Keshavjee S, Hutcheon MA, Singer LG. Upper lobe fibrosis: a new manifestation of chronic allograft dysfunction in lung transplantation. Journal of Heart and Lung Transplantation (in press)

Chapters and Monographs

Singer LG, Weinacker AB, Theodore J. Long- term management and outcomes of heart-lung and lung transplant recipients. In: Heart-Lung and Lung Transplantation 2nd ed. (WA Baumgartner, B Reitz, E Kasper, J. Theodore, eds). W.B. Saunders Company, 2001.

Singer LG. Cost effectiveness and quality of life: benefits of lung transplantation. Respiratory Care Clinics of North America (in press)