| Faculty Research Interests |
| Name |
Hospital Affiliation |
Research Interests |
Methods |
Recent Publi-cations |
Graduate Affiliation |
HSC-Hospital for Sick Children; LKSKI-Li Ka Shing Knowledge Institute; MSB-Medical Sciences Building; MSH-Mount Sinai Hospital; OICR-Ontario Institute For Cancer Research; SB-Sunnybrook;
SMH-St. Michael's Hospital; TGH-Toronto General Hospital; TRI-Toronto Rehabilitation Institute; UHN-University Health Network; WCH-Women's College Hospital; WP-West Park;
IMS-Institute of Medical Science; HPME-Health Policy, Management and Evaluation; GDRS-Graduate Department of Rehabilitation Sciences; Phys-Physiology; Med-Medicine; Anesth-Anesthesia |
Neill Adhikari
neill.adhikari@sunnybrook.ca
Sunnybrook Research Institute |
SB |
- Statins for prevention of sepsis
- Different modalities of renal replacement in acute renal failure in the ICU
- Evidence-based therapy for acute lung injury
|
- Critical care delivery in low-resource settings
- Renal replacement for acute kidney injury in the ICU
- Meta-analysis; Clinical research including observational and randomized designs
|
PubMed search |
|
Monica Avendano
Monica.Avendano@westpark.org |
WP |
- Multidrug-resistant Tuberculosis and Long Term Mechanical Ventilation
|
|
PubMed search |
|
Meyer Balter
mbalter@mtsinai.on.ca |
MSH
UHN |
- Sarcoidosis-clinical data base being established with view to clinical trials and observational studies
- Asthma-education and treatment
- COPD-inflammatory therapy and acute exacerbations
|
- Clinical research - human subjects
|
PubMed search |
|
Jane Batt
Jane.Batt@utoronto.ca
Keenan Research Centre
Toronto Musculoskeletal Centre |
SMH
LKSKI |
- Molecular mediators of muscle atrophy: (i) identification and characterization of new players; (ii) applicability to muscle atrophy associated with human disease (lung)
|
- Molecular techniques applied in vitro, in vivo (animal) and human
|
PubMed search |
IMS |
Matthew Binnie
Matthew.Binnie@uhn.ca |
TGH
UHN |
- Molecular biology connected to lung development, lung inflammation and pulmonary fibrosis
|
- Genetically modified mice, molecular biology, immunohistochemistry
|
PubMed search |
|
Douglas Bradley
douglas.bradley@utoronto.ca
TGRI, UHN
Toronto Rehab
Ontario Health Study
Sleep and Biological Rhythms
Sleep Health & Research Lab |
UHN
MSH
TRI |
- Sleep disordered breathing and cardiovascular diseases
|
- Human investigation including cardio-respiratory and sleep physiology, epidemiology, and clinical trials
|
PubMed search |
IMS |
Karen E. A. Burns
Burnsk@smh.ca
Keenan Research Centre
Canadian Critical Care Trials Group |
SMH |
- Mechanical ventilation and weaning
|
- RCTs
- Observational Studies
- Meta-analyses
- Surveys
|
PubMed search |
|
Charles Chan
charles.chan@uhn.ca
Toronto General Research Institute, UHN |
UHN
TGH |
|
- Human subjects, phase IIb and III clinical trials on new therapeutics
|
PubMed search |
|
Cecilia Chaparro
cecilia.chaparro@uhn.ca
c.chaparro@utoronto.ca
Toronto Adult Cystic Fibrosis Centre
|
UHN
SMH
TGH |
- Outcomes Post-Transplant:
- General Population and Cystic Fibrosis
- Cystic Fibrosis
- Post Transplant Infections
- Complications with B. cepaci
- Immunosuppression in Lung Transplant
|
- Clinical Research
Clinical Trials
|
PubMed search |
|
Kenneth R. Chapman
kchapman@ca.inter.net
Toronto Western Research Institute, UHN Centre for Sleep and Chronobiology |
UHN
TWH
|
- Airways disease
- Asthma
- COPD
- Alpha1 antitrypsin deficiency
- Respiratory health care delivery
- Patient education
- Epidemiology
|
- Clinical trials
- Survey
- Research registry
- Physiologic measurement
|
PubMed search |
IMS |
Chung-Wai Chow
cw.chow@utoronto.ca |
UHN
TGH
MaRS
|
- Function and regulation of the immuno-regulatory protein, Syk, in airway epithelium
- Effects of air pollution on airway inflammation and injury
- The role of Syk in the pathogenesis of chronic lung allograft dysfunction
|
- Molecular biology
- Mouse models of airway inflammation
- Real time air pollution exposure
- Fluorescence cell imaging
- Transwell cell culture
- Primary airway epithelial cell culture
|
PubMed search |
IMS |
Anna Day
a.day@utoronto.ca
Anna.Day@wchospital.ca
Ontario Health Study |
WCH
UHN
MSH |
- Gender and respiratory health with a focus on airways disease
|
- A "'gender lens” approach to identify areas of health and disease where gender has been overlooked and to explore the gaps in our knowledge that can be addressed by a better understanding of the importance of gender differences
|
PubMed search |
|
Claudia Dos Santos
dossantosc@smh.ca
claudia.santos@utoronto.ca
Keenan Research Centre |
SMH
LKSKI |
- Identification of novel molecular targets for therapy of ventilator induced lung injury/ acute respiratory distress syndrome
- Pathogenesis of multi-organ failure in ventilated critically ill patients
|
- Systems biology approach to identification of novel molecular targets for therapy of critically ill patients
- Primarily microarray technology, but including proteomics and metabolomics
- Integrated functional genomics approach to validation (animal model based)
- Translational biology (human/patient based)
|
PubMed search |
|
Marie Faughnan
faughnanm@smh.ca
Keenan Research Centre
HHT Toronto |
SMH |
- Pulmonary arterio-venous malformations
- Hereditary Hemorrhagic Telangiectasia
- Hepatopulmonary syndrome
- COPD
|
- Mechanistic studies in humans
- Database descriptive research
- Clinical trials
|
PubMed search |
|
Niall D. Ferguson
n.ferguson@utoronto.ca
Canadian Critical Care Trials Group |
UHN
MSH |
- Mechanical ventilation: epidemiology; weaning and liberation; extubation and tracheostomy
- Acute respiratory distress syndrome: definitions; ventilatory management; trial esign
- High-frequency oscillatory ventilation
- Physiology in graduate department
|
- Human subjects
- Observational studies
- Systematic reviews
- Randomized controlled trials
|
PubMed search |
|
Bill Geerts
william.geerts@sunnybrook.ca
Sunnybrook Research Institute |
SB |
- Venous thromboembolic disease: epidemiology, diagnosis, treatment, prevention, process of care issues
|
- Clinical trials
- Quality of care studies
|
PubMed search |
HPME |
Andrea Gershon
andrea.gershon@ices.on.ca
Sunnybrook Research Institute
ICES |
SB |
- Chronic Obstructive Pulmonary Disease (COPD)
- Asthma
- Disease Surveillance
- Quality of Care
- Medication Effectiveness and Safety
|
- Health Services Research
- Population Studies
- Health Outcomes research
- Epidemiology
- Clinical Research
|
PubMed search |
HPME |
Shiphra Ginsburg
shiphra.ginsburg@utoronto.ca
The Wilson Centre |
MSH
UHN |
- Medical education
- Professionalism
- Assessment of clinical competence
- Research methods
|
- Mostly qualitative and mixed methods
- Some quantitative; some survey.
|
PubMed search |
Assoc. Faculty, IMS |
Roger Goldstein
rgoldstein@westpark.org |
WP |
- Impact, components, new initiatives and outcome measures in pulmonary rehabilitation.
- Long term management of ventilator assisted individuals in the community and in a ventilator centre
|
|
PubMed search |
IMS |
John Granton
john.granton>@uhn.ca
Toronto General Research Institute, UHN |
UHN
TGH |
- Pulmonary hypertension
- Right heart failure
- Pulmonary embolism
- Acute lung injury
- Heart - Lung interactions
|
- Clinical trials
- Translational research
- Cell based therapy
- Qualitative research
|
PubMed search |
IMS |
Hartmut Grasemann
hartmut.grasemann@sickkids.ca
SickKids Research Institute |
HSC |
- Clinical research studies in chronic pediatric lung diseases (asthma, CF, SCD)
- Non-invasive assessment of airway inflammation.
- L-arginine / arginase / NO synthase pathway in airway disease. Lung transplantation.
|
- Clinic patients (CF, asthma, SCD)
- Research lab: basic techniques (enzymology, blots, processing of clinical samples), transplants
|
PubMed search |
IMS |
Samir Gupta
guptas@smh.ca
Keenan Research Centre |
SMH |
- Knowledge Translation
- E-Health Innovations
- Asthma
- Rare Lung Diseases
- Hepatopulmonary Syndrome
- Pulmonary Vascular Disease
|
- Knowledge Translation methodology
- Retrospective clincial database research
- Controlled Clinical Trials
|
PubMed search |
|
Laura Hawryluck
laura.hawryluck@uhn.ca
Joint Centre for Bioethics |
UHN
SMH |
- End of life issues
- Ethical issues
- Advance care planning
- Conflicts in decision-making
- Medical Education
|
|
PubMed search |
|
Margaret Herridge
Dr.Margaret.Herridge@uhn.ca
Toronto General Research Institute, UHN
Canadian Critical Care Trials Group |
UHN
TGH |
- Long-term outcomes after ARDS, SARS and chronic critical illness
- Creation of clinical pathways for survivors of critical illness and their caregivers
|
- Clinical research including observational and qualitative studies
|
PubMed search |
IMS
GDRS |
Linn Holness
holnessl@smh.ca
Keenan Research Centre
Occupational Cancer Research Centre
Dalla Lana School of Public Health |
SMH |
- Occupational asthma - particularly physician behaviours, practice patterns and prevention
- Involved in linking various researchers and networks through joint projects
- Link between occupational lung and skin disease
|
|
PubMed search |
IMS |
Richard L. Horner
richard.horner@utoronto.ca
Occupational Cancer Research Centre
B.R.A.I.N Platform, Cardiovascular Platform
Sleep and Biological Rhythms |
MSB |
- Sleep and control of breathing
- Neurobiology of sleep and respiratory regulation
- Experimental approaches to increase respiratory muscle activity in sleep
|
|
PubMed search |
IMS
Phys |
Michael Hutcheon
michael.hutcheon@uhn.ca |
UHN
TGH |
- Clinical studies in transplant
|
- Lung mechanics; clinical studies in transplant
|
PubMed search |
|
Brian Kavanagh
brian.kavanagh@sickkids.ca
SickKids Research Institute
Cardiovascular Platform |
HSC |
- Carbon dioxide and critical care
- Ventilator-associated lung injury
|
- Experimental in vivo and in vitro physiology
- Isolated perfused lung, molecular biology
|
PubMed search |
Anesth
Phys
Med |
Neil Lazar
neil.lazar@uhn.ca |
UHN
MSH |
- End of life care / Ethics
|
|
PubMed search |
IMS |
Warren Lee
Leew@smh.ca
warren.lee@utoronto.ca
Keenan Research Centre
Warren Lee Lab |
SMH |
- Regulation and pertubation of endothelial permeability during inflammation
|
- Cell culture, live cell imaging (e.g. spinning disk confocal, TIRFM, FRAP), Electron Microscopy, as well as traditional biochemical and molecular techniques.
- We grow primary human endothelium from lung, skin, and kidney. Mouse models of sepsis and acute lung injury.
|
PubMed search |
IMS |
Richard Leung
richard.leung@utoronto.ca
Keenan Research Centre
Sleep Laboratory at SMH |
SMH |
- Sleep apnea
- Cardiopulmonary interactions
- Sleep and the autonomic nervous system
|
- Human subjects using mostly non-invasive measures including polysomnography, non-invasive continuous blood pressure, and heart rate variability analysis
- Database comprising >10,000 sleep studies for epidemiologic studies
|
PubMed search |
|
Mingyao Liu
mingyao.liu@utoronto.ca
Toronto General Research Institute, UHN
Cardiovascular Platform
Thoracic Surgery at TGH |
UHN
TGH
MaRS
|
- Acute lung injury, signal transduction
|
- Animal models, cell culture
|
PubMed search |
IMS
Phys |
Ted Marras
ted.marras@utoronto.ca
UHN Asthma and Airway Centre |
UHN
TWH |
- Non-tuberculous mycobacteria
- Interstitial Lung Disease
|
|
PubMed search |
|
Sangeeta Mehta
geeta.mehta@utoronto.ca
SMehta@mtsinai.on.ca
Canadian Critical Care Trials Group |
MSH
UHN |
- Mechanical ventilation
- Sedation and delirium in the ICU
- High frequency oscillatory ventilation
- Psychological outcomes following critical illness
|
- RCTs,
- Observational Studies,
- Surveys
|
PubMed search |
|
Sutapa Mukherjee
sutapa.mukherjee@wchospital.ca
Women's College Research Institute
Ontario Health Study |
WCH
UHN
TRI
OICR |
- Sleep and Respiratory Epidemiology, Genetic
- Epidemiology, Biomarkers, Lung malignancy including malignant mesothelioma, Life course
- Epidemiology; Ontario Health Study
|
- Clinical Research, Epidemiology, Translational research; Database management
|
PubMed search |
|
Clodagh Ryan
clodagh.ryan@uhn.ca
Ontario Health Study
Sleep Health & Research Lab |
UHN
TGH
TRI |
- Sleep disordered breathing and cerebrovascular disease
|
- Humans: Spatial and temporal patterns of cerebrovascular response to hypercapnic and hypoxic stimuli in subjects with, and without, obstructive sleep apnea (OSA).
|
PubMed search |
|
Shane Shapera
Shane.Shapera@uhn.ca
Room 9N-971,
585 University Avenue,
Toronto ON M5G 2N2
Ph: (416) 340-4174
Fax: (416) 971-6427
Pager: (416) 790-1492 |
TGH |
- The relationship between Idiopathic Pulmonary
- Fibrosis (IPF) and Gastroesophageal reflux disease (GERD).
|
- Methods: clinic research - database analysis.
|
PubMed search |
|
Christer Sinderby
sinderbyc@smh.ca
Keenan Research Centre |
SMH
LKSKI |
- Neural (sensory-motor) control of mechanical ventilation, patient-ventilator interaction, ventilator induced lung injury.
|
- Experimental in vivo models
- Human physiological studies
|
PubMed search |
|
Lianne Singer
lianne.singer@uhn.ca
Toronto General Research Institute, UHN |
UHN
TGH |
- Lung transplantation outcomes
- Health-related quality of life
- Lung transplant candidate selection and allocation
- E-health (electronic quality of life assessment, patient internet usage, Tele-health clinic visits)
|
- Outcomes research in human subjects
- Quality of life assessment
- Utility
assessment
- Decision analysis
|
PubMed search |
IMS
HPME |
Arthur Slutsky
arthur.slutsky@utoronto.ca
Keenan Research Centre ACAHO
KSU Medical Research Program
The HUB at LKSKI |
SMH |
- Ventilator-induced lung injury
- Mechanisms of injury
- Non-conventional methods of ventilation
- Acute lung injury/ARDS
|
- In vivo physiological models
- Human subjects
- Cell culture
|
PubMed search |
IMS |
Matthew Stanbrook
m.stanbrook@utoronto.ca
Toronto Western Research Institute, UHN |
UHN
TWH |
- Diseases of the airways, particularly COPD and asthma
- Medical journals and knowledge translation
|
- Clinical epidemiology
- Health services research
|
PubMed search |
HPME |
Susan M Tarlo
susan.tarlo@utoronto.ca
Toronto Western Research Institute, UHN
Dalla Lana School of Public Health
Keenan Research Centre |
UHN
SMH
TWH |
- Occupational and environmental lung disease: clinical studies
|
- Human subjects
- Endotoxin assays and biomarkers
- Collaboration with genetic studies
|
PubMed search |
IMS |
Elizabeth Tullis
tullise@smh.ca
Keenan Research Centre
Toronto Adult Cystic Fibrosis Centre |
SMH |
- Adult Cystic Fibrosis (trials of new therapies, health related quality of life, genotype-phenotype relationships)
- CFTR related disorders
|
- Clinical research
- Clinical trials
|
PubMed search |
|
Noe Zamel
noe@zamel.ca
Division of Occupational and Environmental Health |
UHN
MSH
WCH |
- Asthma
- COPD
- Nicotine addiction: pathophysiology and genetics
|
- In-vivo
- Human subjects
- Pulmonary function
- Breath analyses
- Genetic phenotyping
|
PubMed search |
|
