Min Zhuo
Professor, MD
Dr. Min Zhuo is a Professor of Physiology, University of Toronto. He is the Michael Smith Chair in Neuroscience and Mental Health, and the Canada Research Chair Tier I. He earned Ph.D. degree in Pharmacology from University of Iowa. He held a faculty position of full professor at Washington University in St. Louis, before he moved to Toronto. Dr. Zhuo’s research interests are cellular and molecular mechanisms of synaptic plasticity, and their roles in chronic pain. He has published more than 200 articles in professional journals such as Nature, Science, Nature Neuroscience and Neuron. His H-factor is 48. He is the founding editor and editor-in-chief for the online journal of Molecular Pain and Molecular Brain. He was Chang Jiang Scholar in Fudan University (2005-2008) and is currently the WCU_Seoul National University visiting Professor, Korea. In 2009, he has been elected to Fellow of Royal Society of Canada.
University:University of Toronto
Principal Faculty:Faculty of Medicine
Principal Department/Program:Physiology
Telephone:416-978-4018
E-mail Address:min.zhuo@utoronto.ca
Current Grants:
(1) NSEC Discovery grant.
(2) CIHR operating grant.
(3) World-Class University project (Seoul)
Top Awards:
(1) The EJLB-CIHR Michael Smith Chair in Neuroscience and Mental Health (2005-).
(2) Canada Research Chair in Pain and Cognition, Tier I (2005-).
(3) Chang Jiang Visiting Scholar in Neurobiology, Fudan University (2005-2008).
(4) SNU_WCU Professor (2009-).
(5) Fellow of Royal Society of Canada (2009-).
(6) Investigator award (2012).
Key Publications:
(1) Vecsey, C. G., Baillie, G. S., Jaganath, D., Havekes, R., Daniels, A., Wimmer, M., Huang, T., Brown, K. M., Li, X. Y., Descalzi, G., Kim, S. S., Chen, T., Shang, Y. Z., Zhuo, M., Houslay, M. D., & Abel, T. (2009). Sleep deprivation impairs cAMP signalling in the hippocampus. Nature, 461, 1122-1125. http://www.ncbi.nlm.nih.gov/pubmed/19847264
(2) Li, X. Y., Ko, H. G., Chen, T., Descalzi, G., Koga, K., Wang, H., Kim, S. S., Shang, Y., Kwak, C., Park, S. W., Shim, J., Lee, K., Collingridge, G. L., Kaang, B. K., & Zhuo, M. (2010). Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex. Science, 330, 1400-1404. http://www.ncbi.nlm.nih.gov/pubmed/21127255
(3) Wang, H., Xu, H., Wu, L. J., Kim, S. S., Chen, T., Koga, K., Descalzi, G., Gong, B., Vadakkan, K. I., Zhang, X., Kaang, B. K., & Zhuo, M. (2011). Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain. Sci Transl Med., 3(65), 65ra3. http://www.ncbi.nlm.nih.gov/pubmed/21228397
(4) Kim, J. I., Lee, H. R., Sim, S. E., Baek, J., Yu, N. K., Choi, J. H., Ko, H. G., Lee, Y. S., Park, S. W., Kwak, C., Ahn, S. J., Choi, S. Y., Kim, H., Kim, K. H., Backx, P. H., Bradley, C. A., Kim, E., Jang, D. J., Lee, K., Kim, S. J., Zhuo, M., Collingridge, G. L., & Kaang, B. K. (2011) PI3Kγ is required for NMDAR-dependent long-term depression and behavioral flexibility. Nat Neurosci., 14, 1447-1454. http://www.ncbi.nlm.nih.gov/pubmed/22019731
(5) Nicolas, C. S., Peineau, S., Amici, M., Csaba, Z., Fafouri, A., Javalet, C., Collett, V. J., Hildebrandt, L., Seaton, G., Choi, S. L., Sim, S. E., Bradley, C., Lee, K., Zhuo, M., Kaang, B. K., Gressens, P., Dournaud, P., Fitzjohn, S. M., Bortolotto, Z. A., Cho, K., Collingridge, G. L. (2012) Jak/STAT pathway is involved in synaptic plasticity. Neuron, 73, 374-390. http://www.ncbi.nlm.nih.gov/pubmed/22284190