Hance Clarke
MSc, MD, FRCPC
Dr. Hance Clarke is a staff anesthesiologist and the Medical Director of the Pain Research Unit at the Toronto General Hospital. He is actively engaged in research which examines perioperative interventions and the impact that these interventions have on functional recovery after surgery and on the development of persistent chronic post surgical pain. Other areas of his interest include, sleep/pain research, chronic pain research and research into the phenomics and genomics of chronic pain.
University:University of Toronto
Principal Faculty:Faculty of Medicine
Principal Department/Program:Anesthesia and Pain Management
Principal Hospital Appointment(s):Toronto General Hospital, UHN
Telephone:416-340-4800 #6649
Fax Number:416-340-3698
E-mail Address:hance.clarke@utoronto.ca
Current Grants:
(1) Agency: Physicians’ Services Incorporated Foundation Title: The Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain.
(2) Agency: National Institutes of Health Title: Health related quality of life studies after adult to adult live liver donation.
(3) Agency: Pfizer Canada Award: Pfizer Neuropathic Pain Award Title: The Short and Long Term Effects of Perioperative Pregabalin Use on Functional Rehabilitation, Pain Outcomes and Anxiety following Total Hip Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
Top Awards:
(1) Canadian Pain Society: Clinical Pain Management Fellowship Award
(2) Department of Anesthesia, Merit Award- University of Toronto (Research Salary Support)
(3) Canadian Institutes of Health Research (CIHR)
(4) PhD Fellowship Award
(5) Dr. Alan K. Laws Clinician- Scientist Fellowship
Key Publications:
(1) Clarke, H. A., Bonin, R., Orser, B., et al. (2012). The prevention of chronic postsurgical pain using gabapentin and pregabalin: A combined systematic review and meta-analysis. Anesthesia and Analgesia, 115(2), 428-42. http://www.ncbi.nlm.nih.gov/pubmed/22415535
(2) Katz, J., Clarke, H. A., & Seltzer, Z. (2011). Preventive analgesia: Quo Vadimus? Anesthesia and Analgesia, 113(5), 1242-53. http://www.ncbi.nlm.nih.gov/pubmed/21965352
(3) Clarke, H. A., Woodhouse, L. J., Kennedy, et al. (2011). Strategies aimed at preventing chronic post-surgical pain: Comprehensive perioperative pain management after total joint replacement surgery. Physiotherapy Canada, 63(3), 289-304. http://www.ncbi.nlm.nih.gov/pubmed/22654235
(4) Kleiman, V., Clarke, H. A., & Katz, J. (2011). Sensitivity to Pain Traumatization: A higher-order factor underlying pain-related anxiety, pain catastrophizing, and anxiety sensitivity in patients scheduled for major surgery. Pain Research and Management, 16(3), 167-77. http://www.ncbi.nlm.nih.gov/pubmed/21766066
(5) Clarke, H. A., Chandy, T., Srinivas, C., et al. (2011). Epidural Analgesia provides better pain management after live liver donation – A retrospective review. Liver Transplantation, 17(3), 315-23. http://www.ncbi.nlm.nih.gov/pubmed/ 21384514