The University of Toronto Centre for the Study of Pain

155 College Street

Suite 300, Room 302

Toronto, Ontario

M5T 1P8

Tel: 416-946-8270

Fax: 416-978-0817

pain.director@utoronto.ca

UTCSP Research in the Spotlight!

Persistent chest pain: The quest to solve a medical mystery
By Michael McGillion RN, PhD and Heather Arthur PhD, FESC
Guest Co-Editors, “No Amount of Pain is Satisfactory: New Perspectives on Persistent Cardiac Pain,” published in The Canadian Journal of Cardiology www.heartandstroke.com/site/c.ikIQLcMWJtE/b.8030501/k.A78F/Persistent_chest_pain_The_quest_to_solve_a_medical_mystery.htm

 

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Canadian researchers reveal chronic pain may have to do with our genes
www.globalnews.ca/video/pain+gene/video.html
 

 

IASP Global Year Against Headache - October 2011 - October 2012

 

IASP 14th World Congress on Pain


Milan 2012
14th World Congress on Pain
Milano Convention Centre - August 27-31, 2012

Click HERE for further information, registration and program updates, plea

 

"Why Your Doctor Thinks You're Crazy: Is Your Chronic Pain a Disease?"


The Dr. Oz Show explores the subjet of chronic pain.  Click on the link to view:  watch.ctv.ca/#clip539678

Pain in the News

2012-04-02 : Primary and metastatic cancers that affect bone are frequently associated with severe and intractable pain. The mechanisms underlying the development of bone cancer pain are largely unknown....
2012-03-29 : It has been reported that the P2Y12 receptor (P2Y12R) is involved in satellite glial cells (SGCs) activation, indicating that P2Y12R expressed in SGCs may play functional roles in orofacial neuropathic pain mechanisms. However, the involvement of P2Y12R in orofacial neuropathic pain mechanisms is still unknown....
2012-03-28 : Acute or chronic tissue damage induces an inflammatory response accompanied by pain and alterations in local tissue temperature. Recent studies revealed that the transient receptor potential A1 (TRPA1) channel is activated by a wide variety of substances that are released following tissue damage to evoke nociception and neurogenic inflammation....
2012-03-25 : Interstitial cystitis/painful bladder syndrome (IC/PBS), is a severely debilitating chronic condition that is frequently unresponsive to conventional pain medications. The etiology is unknown, however evidence suggests that nervous system sensitization contributes to enhanced pain in IC/PBS....
2012-03-25 : Members of the degenerin/epithelial (DEG/ENaC) sodium channel family are mechanosensors in C elegans, and Nav1.7 and Nav1.8 voltage-gated sodium channel knockout mice have major deficits in mechanosensation. beta and gamma ENaC sodium channel subunits are present with acid sensing ion channels (ASICs) in mammalian sensory neurons of the dorsal root ganglia (DRG)....
2012-03-24 : Despite decades of intense research efforts, actions of acute opioids are not fully understood. Increasing evidence suggests that in addition to well-documented antinociceptive effects opioids also produce paradoxical hyperalgesic and excitatory effects on neurons....