Bernadene A. Magnuson, Ph.D., FATS
Adjunct Associate Professor
Department of Nutritional Sciences

Ph: 416.978.1832; 416.986.7092
Fax: 416.978.5882
bmagnuson@utoronto.ca




Primary Affiliations:

• Department of Nutritional Sciences
  

Other Affilliations:

• Co-Director, Program in Food Safety, Nutrition and Regulatory Affairs (PFSNRA)

Education/Degrees:

• Home Economics Food Science and Nutrition – Distinction (University of Saskatchewan);
• M.Sc. Toxicology (University of Saskatchewan);
• Ph.D. Food and Nutritional Sciences (University of Manitoba)
  

Awards/Recognition:

• 2011   Fellow, Academy of Toxicological Sciences
• 2007   Distinguished Lecturer, IFT
• 2006   Outstanding Division Member, Toxicology and Safety Evaluation Division of IFT
• 2005   Selected for Who’s Who among American Teachers
• 2004   Food and Drug Administration’s Commissioner’s Special Citation Award
  as a member of the Risk Assessment Education Program
• 2004   Finalist, Inventor of the Year, University of Maryland.
• 2002-05 Selected for Who’s Who in Medicine and Healthcare
• 1998   Leadership Idaho Agriculture, Best Speaker Award and selected as Class Representative to address Governor Phil Batt
• 1993-95   Health Services Utilization and Research Commission Research Fellowship
• 1992  Canadian Society of Nutritional Sciences Graduate Student Research Award
• 1990-91   University of Manitoba Graduate Scholarship (declined)
• 1990-92   Manitoba Health Research Council Studentship
• 1989-90   Gerry Vogel Scholarship for Outstanding Graduate Student
• 1983-84   Elizabeth Helen McLeod Scholarship
• 1983-84  University of Saskatchewan Graduate Scholarship
• 1983-84   John and Mary Spinks Scholarship
• 1982-83  University of Saskatchewan Graduate Scholarship
• 1982-83   John and Mary Spinks Scholarship
• 1982-83   Hope Hunt Scholarship 1982-83  Elizabeth Helen McLeod Scholarship
• 1979-80  University Undergraduate Scholarship
• 1979-80   Proctor and Gamble Bursary
• 1979-80   Hannon Travel Scholarship
• 1979-80   Canadian Home Economics Association Incentive Award
• 1978-79   Hannon Undergraduate Scholarship
• 1978-79   Bertha Oxner Scholarship
• 1976-77   Mary Chamard Memorial Scholarship

Professional Memberships:                                                    

Appointments

• Sept 2011- Co-Director, University-Industry Program in Food Safety, Nutrition and Regulatory Affairs (PFSNRA), University of Toronto
• July 2011- President, BMagnuson Consulting, Oakville, ON
• Jan 2008- Associate Adjunct Professor, Nutritional Sciences, Faculty of Medicine,
  University of Toronto
• Jan 2008-June 2011 Senior Scientific & Regulatory Consultant, Food and Nutrition Group, CANTOX Health Sciences International, Mississauga, ON
• May 2006-Sept 2006 Senior Toxicologist, Burdock Group, Washington DC
• May 2005-May 2006 Toxicologist, Burdock Group, Washington DC
• Dec 1999-Dec 2007 Assistant Professor, Nutrition and Food Science, University of Maryland
• Jan 1995-Dec 1999 Assistant Professor, Food Science and Toxicology, University of Idaho
• May 1993-Jan 1995 Postdoctoral fellow, Saskatoon Cancer Centre, University of Saskatchewan
• 1987-92 Lecturer, Food Science, University of Manitoba
• 1986-89 Program Co-ordinator, Continuing Education Division, University of Manitoba
• 1984-85 Research Associate, Applied Microbiology Food Science, University of Saskatchewan
• 1981-82 Food Product Development Research Technician, POS Pilot Plant Corporation, Saskatoon, SK, Canada
• 1980-81 Quality Assurance Laboratory Technician, Mayfair Hams, Bendigo, Australia Membership
• 2010- Council Member, Society of Toxicology (SOT) Food Safety Specialty Section (FS3)
• 2008- Member, International Society of Regulatory Toxicology and Pharmacology
• 2007- Member, Canadian Nutrition Society/la Société canadienne de nutrition (CNS/SCN)
• 2007- Member, Society for Risk Analysis
• 2006- Member - Institute of Food Technology (IFT) NanoScience Panel
• 2005- Full Member, Society of Toxicology
• 2004-06 Member, The International Society for Preventive Oncology
• 1995- Professional Member, Institute of Food Technology
• 1995-2003 Full Member, American Association for Cancer Research
• 1985- Member, Society of Toxicology of Canada Editorial Boards
• 2007- Associate Editor, Food Analytical Methods
• 2004- Editorial Board, Journal of Food Protection
• 2008-09 Member of the International Advisory Board for the Advanced Food Materials Network
• 2008-09 Member of the Cross-Industry Nanomanufacturing Group, National Institute of Standards and Technology
• 2008-09 Expert Panellist - Evidence Analysis Workgroup, American Dietetic Association
• 2008-09 Expert panel member, IFT Scientific report on Food Safety
• 2005-08 Grant reviewer for the Ohio Agricultural Research and Development Centers Research Enhancement Competitive Grants Program
• 2004 Grant reviewer for USDA National Research Initiative proposals
• 2004 Panel member NIH NIDRC Special Grants Review Committee (Feb 19-20)
• 2003 Grant reviewer for United States – Israel Bi-national Agricultural Research
  and Development Fund
• 1999 Reviewer for USDA of the Food Quality Protection Act Science Policy on Dietary Exposure to Pesticides
  
  Ad hoc reviewer for numerous journals including: Toxicology, Toxicological Sciences, Food and Chemical Toxicology, Journal of Agricultural and Food Chemistry, Nutrition and Cancer, Carcinogenesis, Oncogene, Oncology, Cell Calcium, Pathology, Cancer Letters, Journal of Food Science, Journal of Food Quality, Molecular Carcinogenesis, and others.

Research:

My research interests have been in the area of diet and cancer and I am now interested in the new and exciting area of nanotechnology and its role in nutrition. In the past, I managed a research team, including 2 postdoctoral fellows, 6 research associates, mentored research of 8 Ph.D. and M.Sc. students, and 14 undergraduate students. I have also been awarded:


• a contract to conduct a Comprehensive Review and Analysis of Safety Implications of Nanoscale Science and Technology in Food by the US Institute of Food Technologists and the Grocery Manufacturers Association of America; and
  
  
• over one million dollars from NIH, USDA, American Cancer Society, American Institute for Cancer Research, The Cancer Prevention Research Association, Joint Institute of Food Safety and Nutrition, various commodity groups, and industry.

Recent Publications:                                                   

Papers in refereed journals (2007 – present)

1. Haighton LA, Lynch BS, Magnuson BA, Nestmann ER. A re-assessment of risk associated with dietary intake of Ochratoxin A based on a lifetime exposure model, Crit Rev in Tox. In press.
2. Card JW, Magnuson BA, (2011) A Review of the Efficacy and Safety of Nanoparticle-Based Oral Insulin Delivery Systems. Am J Physiol Gastrointest Liver Physiol. 2011 Sep 15.
3. Magnuson BA, Jonaitis TS, Card JW (2011). A Brief Review of the Occurrence, Use, and Safety of Food-Related Nanomaterials. J. Food Sci. 76(6) p. R126-133.
4. Card JW, Jonaitis TS, Tafazoli S, Magnuson BA (2011). An appraisal of the published literature on the safety and toxicity of food-related nanomaterials. Crit Rev Toxicol 41(1):22-51.
5. Wong AW, Magnuson BA, Nakagawa K, Bursey RG (2011). Oral subchronic and genotoxicity studies conducted with the amino acid, L-glutamine. Food Chem Toxicol 49 (9):2096-102.
6. Card JW, Magnuson BA (2010). A method to assess the quality of studies that examine the toxicity of engineered nanomaterials. Int J Toxicol 29(4) 402-410.
7. Magnuson B (2010). Aspartame - facts and fiction. NZ Med J 123(1311):53-57.
8. Jonaitis T, Card J, Magnuson B (2010). Concerns regarding nano-sized titanium dioxide dermal penetration and toxicity study. Toxicol Lett 192(2):268-269.
9. Bidlack WR, Birt D, Borzelleca J, Clemens R, Coutrelis N, Coughlin JR, Dunaif JE, Ebert A, Hall R, Heimbach JH, Helferich W, Magnuson B, McColl DB, McQuate RS, Munro I, Petersen B, Roberts A, Scimeca J, Slayne M, Trautman T, contributors (2009). Making decisions about the risks of chemicals in foods with limited scientific information (An IFT Expert Report). Compr Rev Food Sci Food Safety 8:269-303.
10. Bugusu B, Meija C, Magnuson B, Tafazoli S (2009). Global regulatory policies on food nanotechnology. Food Technol 63(5):24-28.
11. Card JW, Magnuson BA (2009). Proposed minimum characterization parameters for studies on food and food-related nanomaterials. J Food Sci 74(8):vi-vii.
12. Kwon Y, Magnuson BA (2009). Age-related differential responses to curcumin-induced apoptosis during the initiation of colon cancer in rats. Food Chem Toxicol 47(2):377-385.
13. Francke-Carroll S, Daly K, Magnuson BA (2008). Underlying age- related liver pathology increases toxicity of azoxymethane in F344 female rats in an aging study on diet and colon cancer. Int J Food Sci Technol Nutr 2:1-8.
14. Fujii H, Nishioka H, Wakame K, Magnuson BA, Roberts A (2008). Acute, subchronic and genotoxicity studies conducted with Oligonol, an oligomerized polyphenol formulated from lychee and green tea extracts. Food Chem Toxicol 46(12):3553-3562.
15. Jing P, Bomser JA, Schwartz SJ, He J, Magnuson BA, Giusti MM (2008). Structure-function relationships of anthocyanins from various anthocyanin-rich extracts on the inhibition of colon cancer cell growth. J Agric Food Chem 56(20):9391-9398.
16. Magnuson B, Williams GM (2008). Carcinogenicity of aspartame in rats not proven [with response from Morando Soffritti]. Environ Health Perspect 116(6):A239-A240.
17. Choi EH, Ok HE, Yoon Y, Magnuson BA, Kim MK, Chun HS (2007). Protective effect of anthocyanin-rich extract from bilberry (Vaccinium myrtillus L.) against myelotoxicity induced by 5-fluorouracil. Biofactors 29(1):55-65.
18. Daly KT, Tracy AC, Malik M, Wang T, Francke-Carroll S, Magnuson BA (2007). Enhanced estrogenic responses and sensitivity to azoxymethane following dietary soy isoflavone supplementation in older female rats. Food Chem Toxicol 45(4):628-637.
19. Kwon Y, Magnuson BA (2007). Aging alters acute apoptotic response to azoxymethane in the colon of rats. Exp Gerontol 42(12):1154-1161.
20. Kwon Y, Magnuson BA (2007). Effect of azoxymethane and curcumin on transcriptional levels
    of cyclooxygenase-1 and -2 during initiation of colon carcinogenesis. Scand J Gastroenterol 42(1):72-80.
21. Magnuson BA, Appleton J, Ames GB (2007). Pharmacokinetics and distribution of [35S]methylsulfonylmethane following oral administration to rats. J Agric Food Chem 55(3):1033-1038.
22. Magnuson BA, Appleton J, Ryan B, Matulka RA (2007). Oral developmental toxicity study of methylsulfonylmethane in rats. Food Chem Toxicol 45(6):977-984.
23. Magnuson BA, Burdock GA, Doull J, Kroes RM, Marsh GM, Pariza MW, Spencer PS, Waddell WJ, Walker R, Williams GM (2007). Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies. Crit Rev Toxicol 37(8):629-727.

Book chapters (2007 – present)

1. Magnuson BA, Bouwmeester H (2011). Toxicology of nanomaterials in food. (Chapter 10). In: Norde W, Fisher A, Frewer L, Kamper F, editors. Nanotechnology in the Agri-food Sector. Implications for the Future. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, pp. 173-190.
2. Magnuson BA (2010). Contaminants of concern. In: Institute of Medicine. “Providing Healthy and Safe Foods as We Age”. Washington (DC): National Academies Press (NAP).
3. Ottesen AR, Magnuson BA (2009). Naturally occurring toxins in plants. In: Juneja VK, Sofos JN, editors. Pathogens and Toxins in Foods: Challenges and Interventions. Washington (DC): American Society for Microbiology (ASM) Press, pp. 301-313.

Papers in Conference Proceedings (2007 – present)

1. Magnuson BA (2009). Nanoscale materials in foods: Existing and potential sources (Chapter 4). In: Al-Taher F, Jackson L, DeVries JW, editors. Intentional and Unintentional Contaminants in Food and Feed. (ACS Symposium Series, Vol 1020). Washington (DC): American Cancer Society (ACS), pp. 47-55.
2. Magnuson BA (2008). Issues and challenges for nanoscale science in food applications. World Food Sci 4(Apr./May).

Inventions and Patents

1. US Patent Application No. 11/106240. Application pending. University of Maryland Intellectual Property Disclosure. “Combinational fruit extract and 5-fluorouracil treatment for colon cancer”. Inventors: Magnuson BA, Yu T.
2. US Patent. University of Maryland Intellectual Property Disclosure. “Chemopreventive properties of anthocyanin-rich extracts”. Inventors: Magnuson BA, Giusti MM, Malik M, Zhao C. 03/2002. US Patent No 8034388. Issued Oct 11, 2011.
3. European Patent Office, Patent NR. 99309933.2-2201; "System and method for identifying the geographic origin of a fresh commodity" Anderson KA, Smith B, Magnuson B. Florida Dept. of Citrus, 29/02/00.
4. U.S. Patent and Trademark Office Serial No. Patent No. 09/210,358; "System and Method for Identifying the Geographic Origin of a Fresh Commodity". Anderson KA. Smith BW, Magnuson B., and Florida Dept. of Citrus and Idaho Potato Commission, filed 12/11/98
   
   PubMed