Bernadene A. Magnuson, Ph.D.

Adjunct Associate Professor Department of Nutritional Sciences Senior Scientific and Regulatory Consultant Cantox Health Science International 2233 Argentia Road, Suite 308, Mississauga, ON L5N 2X7 Tel: (905) 542 2900 Fax: (905) 542 1011 E-mail: bmagnuson@cantox.com

Research

My research interests have been in the area of diet and cancer and I am now interested in the new and exciting area of nanotechnology and its role in nutrition.

Selected Publications

• Y. Kwon, M. Malik and B.A. Magnuson. 2004. Inhibition of colonic aberrant crypt foci by curcumin in rats is affected by age. Nutrition and Cancer 48(1):37-43.
• M. Malik and B.A. Magnuson, 2004. Rapid method for identification of chemopreventive compounds using multiplex RT-PCR for cyclooxygenase mRNA expression. Cancer Detection and Prevention. 28(4): 277-282.
  *Selected as one of the best papers published in this journal in 2004. Documentation from the editor is attached.
• C. Zhao, M. Malik, M.M. Giusti, M.P. Moyer and B.A. Magnuson. 2004. Comparison of various anthocyanin-rich extracts on the growth of colonic cancer cells. Journal of Agricultural and Food Chemistry.  52:6122-6128.
• J. He, B.A. Magnuson and M. M. Giusti. 2005.  Analysis of anthocyanins in rat intestinal contents - impact of anthocyanin chemical structure on fecal excretion. Journal of Agricultural and Food Chemistry. 53(8):2859-66.
• G. Lala, M. Malik, C. Zhao, Y. Kwon, H. Je, M.M. Giusti and B.A. Magnuson. 2006. Anthocyanin-rich extracts inhibit multiple biomarkers of colonic cancer in rats. Nutrition and Cancer. 54(1):84-93.
• J. He, B.A. Magnuson, G. Lala, Q. Tian, S.J. Schwartz and M.M. Giusti. 2006. Intact anthocyanins and metabolites in rat urine and serum after three months of anthocyanin supplementation Nutrition and Cancer. 54(1):3-12.
• Y. Kwon and B.A. Magnuson. 2007. Effect of azoxymethane and curcumin on transcriptional levels of cyclooxygenase-1 and –2 during initiation of colon carcinogenesis. Scandinavian Journal of Gastroenterology. 42 (1):72-80.
• K. Daly, A. Tracy, S. Francke-Carroll, T. Wang, M. Malik and B.A. Magnuson. 2007. Enhanced estrogenic responses and sensitivity to azoxymethane following dietary soy isoflavone supplementation in older female rats. Food and Chemical Toxicology. 45(4):628-37.
• B.A. Magnuson, J. Appleton and B. Ryan. 2007. Reproductive toxicity of methylsulfonylmethane following oral administration to rats. Food and Chemical Toxicology. 45(6):977-84.
• B.A. Magnuson, J. Appleton and G.B. Ames. 2007. Pharmacokinetics and distribution of [35S]-methylsulfonylmethane following oral administration to rats. Journal of Agricultural and Food Chemistry. Feb 7;55(3):1033-8.
• Choi, E.H., Ok, H.E., Yoon, Y, Magnuson, B.A., Kim, M.K., and Chun, H.S. 2007. Protective effect of anthocyanin-rich extract from bilberry (Vaccinium myrtillus L.) against myelotoxicity induced by 5-fluorouracil. Biofactors 29(1):55-65.
• B.A. Magnuson, G.A. Burdock, J. Doull, R.M. Kroes, G.M. Marsh, M.W. Pariza, P.S. Spencer, W.J. Waddell, R. Walker, G.M. Williams. 2007. Aspartame: A safety evaluation based on current use levels, regulations, toxicological and epidemiological studies. Critical Reviews in Toxicology. 37(8):629-727.