Carol E. Greenwood, Ph.D.

Professor Department of Nutritional Sciences Associate Director of KLARU Baycrest Centre for Geriatric Care Faculty of Medicine University of Toronto FitzGerald Building, Room 430 150 College Street Toronto ON M5S 3E2 CANADA Tel: (416) 978 4261 Fax: (416) 978 5882 E-mail: carol.greenwood@utoronto.ca

Research

The overall goal of my research programme is to understand the brain's sensitivity to nutrient intake and how this changes with aging. The key nutrients examined include amino acids, fatty acids and glucose with modulation in feeding behaviour and cognitive performance being the main behavioural outcomes monitored. Our cognitive studies focus on cognitive decline with aging, its linkage to chronic diet and the development of insulin resistance, and its modulation by acute nutrient intake. Feeding behavioural studies focus on disruptions in appetite regulation in both healthy seniors as well as those with neurodegenerative disorders including Alzheimer disease.

Selected Publications

• Kaplan, R.J. Greenwood CE, C.E., Winocur, G., Wolever, T.M.S. Cognitive performance is associated with glucose regulation in healthy elderly persons and can be enhanced with glucose and dietary carbohydrates. Am. J. Clin. Nutr. 72: 825-836, 2000.
• Winocur W, Greenwood CE. The effects of high fat diets and environmental influences on cognitive performance in rats. Behav. Brain Res. 101:153-161, 1999.
• Greenwood CE, Winocur, G. Glucose treatment reduces memory deficits in young adult rats fed high fat diets. Neurobiol. Learning Memory 75:179-189, 2001.
• Dyer, S, Greenwood, CE. Is breakfast the best consumed meal of the day in institutionalized elderly with high level cognitive impairment? J. Amer. Geriatr. Soc. (In press).
• Young, K.W.H., Greenwood C.E. Shift in diurnal feeding patterns in nursing home residents with Alzheimer disease. J. Geriatr. (In press).