McLaughlin-McEwen Pluripotent Stem Cell Core Training Facility

Contact for Website

Prachi Khandekar

11th Floor Donnelly CCBR
160 College St.
Toronto, Ontario, Canada
M5S 3E1
Email

PH: 416.978.0553
FX: 416.978.2666

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McLaughlin-McEwen Pluripotent Stem Cell Core Training Facility

APPROVALS

Before you can obtain the cells from our Core Training Facility, you must first complete a process of Ethics Approvals through the Research Ethics Board (REB).

Next, you must have approval from your own institution's Research Ethics Board to have ethics approval for human subjects. The University of Toronto's REB forms can be found here.


Be sure to download the appropriate forms for the faculty you are in. Please consult your own institution's Research Ethics Board for their forms.


Thirdly, the Stem Cell Oversight Committee must give approval and can only be applied for after your home institution's REB gives their approval for your proposed work. Consult their website for full details.


Please click here for a copy of the Stem Cell Oversight Committee's Application for Review.

 

CA1/CA2 Cells

Because our CA1/CA2 cells were originally obtained from Mount Sinai Hospital, a Material Transfer Agreement (MTA) must be completed. To obtain an MTA, contact Mt. Sinai's Office of Technology Transfer and Industry Liaison at:

Office of Technology Transfer & Industrial Liaison
600 University Avenue, Room 843
Toronto, Ontario, Canada M5G 1X5
Tel. 416.586.4800 ext. 3117
Fax 416.586.8844
tacorda@mshri.on.ca

Please note, this step is for CA1/CA2 cells only. For all other cells another MTA will be provided.

 

WiCell derived cell lines available through the Core Facility

 

The University of Toronto, on behalf of the McLaughlin-McEwen Pluripotent Stem Cell Core Training Facility has entered into a memorandum of understanding (MOU #08-W320) with the WiCell Research Institute to obtain materials (cell lines) from WiCell.  The Core Facility will bank and distribute certain lines derived at WiCell as well as mediate their acquisition from WiCell.  If you wish to order cells, please read the MOU and implementing letter (see PDF).  Also, fill out the Simple Letter Agreement (SLA, available through our website) and return it (along with accompanying documentation) to the Core Facility.  The Core Facility will collect all SLAs and forward them to WiCell for execution.  Be advised that the Core Facility will require a copy of all supporting documents (ie. SCOC approval) that were sent to WiCell as well as the final signed SLA for its own records.  Materials ordered through the Facility will not be released until a copy of all these documents are on file.

Once a year, before May 1st, the annual certification (available through our website) will have to be completed and sent to the Core Facility, which will forward a copy to WiCell, as per terms described in the MOU.

CIHR UPDATES


Read CIHR's updated guidelines for Human Pluripotent Stem Cell Research.

Read CIHR article about the "Science of Stem Cells"

Download the Simple Letter Agreement for Biological Material Transfer form. This form must be filled out before the McLaughlin Centre for Molecular Medicine (MCMM) can distribute biological material. Please note that the $500 fee may be waived at our discretion.