Faculty Profile - Dr. Bernhard Ganss

Dr. Bernhard Ganss
Associate Professor
Matrix Dynamics Group

150 College Street
FitzGerald Building, Room 234
Toronto, Ontario, Canada
M5S 3E2

Phone: 416-978-8728
Fax: 416-978-5956
b.ganss@utoronto.ca
http://matrixdynamics.ca

Current academic / hospital appointments

• Associate Professor, Department of Biological and Diagnostic Sciences, Faculty of Dentistry, University of Toronto
• Associate Member, Matrix Dynamics Group

Education

• 1985 - B.Sc. Chemistry, University of Würzburg, Germany
• 1989 - M.Sc. Chemistry, University of Regensburg, Germany
• 1993 - Ph.D. Molecular Biology, Max Planck Institute and University of Regensburg, Germany

Courses

Undergraduate: "Biological Basis of Oral Health and Disease" (DEN 121H1); Co-ordinator of Lab component.

Graduate/Postgraduate: "Biology of Connective Tissue" (DEN1080Y).

Research interests

• molecular biology / regulation of gene transcription
• developmental biology of mineralized connective tissue (tooth, bone, cartilage)
• molecular genetic strategies for tissue regeneration

Recent publications

• Comparative Temporospatial Expression Profiling of Murine Amelotin Protein during Amelogenesis. Somogyi-Ganss E, Nakayama Y, Iwasaki K, Nakano Y, Stolf D, McKee MD, Ganss B. Cells Tissues Organs. 2011 Sep 9.
• Characterisation of the constitutive over-expression of AJ18 in a novel rat stromal bone marrow cell line (D8-SBMC). Jheon A, Bansal AK, Zhu B, Ganss B, Cheifetz S, Sodek J. Arch Oral Biol. 2009 Aug;54(8):705-16. .
• Simultaneous PKC and cAMP activation induces differentiation of human dental pulp stem cells into functionally active neurons. Király M, Porcsalmy B, Pataki A, Kádár K, Jelitai M, Molnár B, Hermann P, Gera I, Grimm WD, Ganss B, Zsembery A, Varga G. Neurochem Int. 2009 Sep;55(5):323-32.
• Accessibility of ³H-secoisolariciresinol diglycoside lignan metabolites in skeletal tissue of ovariectomized rats. Sacco SM, Thompson LU, Ganss B, Ward WE. J Med Food. 2011 Oct;14(10):1208-14.
  

Awards and Honours

1998: Young Investigator's Award , American Academy of Orthopaedic Surgeons

Students

• Nastaran Abbarin, M.Sc. (Ph.D. Student) from 09/2011: Novel genes of the enamel gene cluster: Implications for biomineralization
  
  

* Presently accepting students for supervision in the areas of molecular, cell, and developmental biology, biochemistry, molecular genetics

Current research grants

05/2011 - 04/2016: discovery grant (NSERC)
Title: Novel genes of the enamel gene cluster: Implications for biomineralization
Award: $180,000
Principal Investigator: Bernhard Ganss