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Selected publications from the Boone Lab, most recent onwards.

For a complete list of publications please visit PubMed.

2007

Boone C, Bussey H, Andrews BJ.
Exploring genetic interactions and networks with yeast.
Nat Rev Genet. 2007 Jun;8(6):437-49.
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2006

Parsons, A.B., Lopez, I. E. Givoni*, D. E. Williams, C. Gray4, J. Porter, G. Chua, R. Sopko, R. L. Brost, C-H Ho, J. Wang, T. Ketela, C. Brenner, J. A. Brill, G. E. Fernandez, T. C. Lorenz, G. S. Payne, S. Ishihara, Y. Ohya, B. Andrews, T. R. Hughes, B. J. Frey, T. R. Graham, R. J. Andersen, C. Boone (2006).
Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast.
Cell 126: 611-625.
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Sopko R, Huang D , Preston N , Chua G , Papp B , Kafadar K , Snyder M , Oliver SG , Cyert M , Hughes TR , Boone C , Andrews B (2006).
Mapping Pathways and Phenotypes by Systematic Gene Overexpression.
Mol Cell. 21:319-330.
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Alto, N.M., F. Shao, C. S. Lazar, R. L. Brost, G. Chua, S. Mattoo, S. A. McMahon, P. Ghosh, T. R. Hughes, C. Boone, and J. E. Dixon (2006).
Identification of a Bacterial Type III Effector Family with G-protein Mimicry Functions
Cell 124:133-145.
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2005

Davierwala AP, Haynes J , Li Z , Brost RL , Robinson MD , Yu L , Mnaimneh S , Ding H , Zhu H , Chen Y , Cheng X , Brown GW , Boone C , Andrews BJ , Hughes TR . (2005).
Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.
Nat Genet. 37:1147-52.
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Zhang L.V., O.D. King, S.L. Wong, D.S. Goldberg, A.H. Tong, G. Lesage, B. Andrews, H. Bussey, C. Boone, F.P. Roth (2005).
Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network.
J Biol. 4:6. Epub 2005 Jun 1.
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Chang, M., M. Bellaoui, C. Zhang, R. Desai, P. Morozov, L. Delgado-Cruzata, R. Rothstein, G.A. Freyer, C. Boone, G.W. Brown (2005).
RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex.
EMBO J. 24:2024-33. Epub 2005 May 12.
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2004

Wong, S. L., L. V. Zhang, A. H. Y. Tong, Z. Li, D. S. Goldberg, O. D. King, G. Lesage, M. Vidal, B. Andrews, H. Bussey, C. Boone, and F. P. Roth (2004),
Combining biological networks to predict genetic interactions.
Proc. Natl. Acad. Sci. USA 101: 15682–15687.
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Xu, H., C. Boone, H. L. Klein (2004).
Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage.
Mol Cell Biol . 24 , 7082-7090.
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Tong, A. H. Y.*, G. Lesage *, G. Bader, H. Ding, H. Xu, X. Xin, J. Young et al., C. G. Burd, S. Munro, C. Sander, J. Rine, J. Greenblatt, M. Peter, A. Bretscher, G. Bell, F. P. Roth, G. Brown, B. Andrews† , H. Bussey† , C. Boone † (2004).
Global Mapping of the Yeast Genetic Interaction Network.
Science 303:808-813.
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Nelson, B., A. B. Parsons, M. Evangelista, K. Schaefer, K. Kennedy, S. Ritchie, T. L. Petryshen, C. Boone, (2004).
Fus1p Interacts with Components of the Hog1p MAPK and Cdc42p Morphogenesis Signaling Pathways to Control Cell Fusion During Yeast Mating.
Genetics 166: 67-77 .
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Parsons, A., Brost, R., Ding, H., Li, Z., Zhang, C., Sheikh, B., Brown, G., Kane, P., Hughes, T., Boone, C. (2004).
Integration of chemical-genetics and genetic interaction data links bioactive compounds to cellular target pathways.
Nat. Biotech 22: 62 -69
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2003

Roemer, T., B. Jiang, J. Davison, T. Ketela, K. Veillette, A. Breton, F. Tandia, A. Linteau, S. Sillaots, C. Marta, N. Martel, S. Veronneau, S. Lemieux, S. Kauffman, J. Becker, R. Storms, C. Boone, H. Bussey. (2003).
Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery.
Mol Microbiol 50, 167-181.
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Nelson, B. *, C. Kurischko*, J. Horecka, M. Mody, P. Nair, L. Pratt, A. Zougman, L. McBroom, T. R. Hughes, C. Boone†, F. C. Luca† (2003).
RAM: a Conserved Signaling Network that Regulates Ace2p Signaling Activity and Polarized Morphogenesis.
Mol Biol Cell. 14, 3782-37803
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Goehring, A., S., D. A. Mitchell, A. H. Y. Tong, M. Keniry, C. Boone, and G. F. Sprague, Jr. (2003)
Ste20p, a p21-Activated Protein Kinase, in Polarisome Activation
Mol. Biol. Cell 14:1501-1516.
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2002

Jorgensen, P., B. Nelson, M. D. Robinson, Y. Chen, B. Andrews, M. Tyers, and C. Boone (2002).
High Resolution Genetic Mapping with Ordered Arrays of S. cerevisiae Deletion Mutants.
Genetics 162:1091-1099.
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Pruyne D.*, M. Evangelista*, C. Yang, E. Bi, S. Zigmond, A. Bretscher†, C. Boone† (2002).
Role of Formins in Actin Assembly: Nucleation and Barbed End Association.
Science 297:612-615.
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Tong A .H.Y.*, B. Drees *, G. Nardelli *, G. D. Bader*, B. Brannetti, L. Castagnoli, M. Evangelista, S. Ferracuti, B. Nelson, S. Paoluzi, M. Quondam, A. Zucconi, C. W. V. Hogue, S. Fields†, C. Boone†, G. Cesareni† (2002).
A Combined Experimental and Computational Strategy to Define Protein Interaction Networks for Peptide Recognition Modules.
Science 295:321-324.
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Evangelista M*., D. Pruyne, D*. C. Amberg, C. Boone†, A. Bretscher† (2002).
Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast.
Nature Cell Biology 4:32-41.
(* authors contributed equally to this work; †corresponding authors)
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2001

Tong A. H. Y., M. Evangelista, A. B. Parsons, H. Xu, G. D. Bader, N. Page, M. Robinson, S. Raghibizadeh, C. W. V. Hogue, H. Bussey, B. Andrews, M. Tyers, C. Boone (2001).
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants.
Science 294:2364-2368.
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2000

Roberts, C*. J., B. Nelson*, M. J. Marton, R. Stoughton, M. R. Meyer, H. A. Benett, Y. D. He, H. Dai, W. L. Walker, T. R. Hughes, M. Tyers, C. Boone † , and S. Friend † (2000).
Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles.
Science 287: 873-880.
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1997

Evangelista M., K. Blundell, M.S. Longtine, C. J. Chow, N. Adams, J. R. Pringle, M. Peter, and C. Boone (1997).
Bni1p, a yeast formin linking Cdc42p and the Actin cytoskeleton during polarized morphogenesis.
Science 276: 118-122.
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For a complete list of publications please visit PubMed.

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