Biological Therapeutics and Cancer: Basic Science, Development, Delivery, and Clinical Evaluations
Friday, November 4, 2011, 9:00am to 6:00pm
Health Sciences Building Auditorium, University of Toronto, 155 College St, Room 610
Program
Symposium 1 - 9:00am to 10:45am - Basic science and cancer
Session I: Jonathan D. Licht, M.D. (Northwestern University Feinberg School of Medicine), “Targeting the MMSET Protein in Multiple Myeloma”
Session II: Riccardo Alessandro, Ph.D. ( University of Palermo, Italy), “Characterization, Functional Analysis and Drug Manipulation of Exosomes in CML”
Coffee Break - 10:45am to 11:00am
Symposium 2 - 11:00am to 12:45pm - Strategies/experiences in Biotherapeutic Drug Development
Session I: David Stojdl, PhD (Children's Hospital of Eastern Ontario, University of Ottawa), "Discovery and Development of Oncolytic Rhabdoviruses"
Session II : John E. Shively, PhD (City of Hope), “Imaging and Therapy with Radiolabeled Antibodies”
Lunch/Poster Session – 12:45pm to 2:00pm
Symposium 3 – 2:00pm to 3:15pm - Drug delivery
Session I: Dr. Pieter Cullis (UBC), “Design of Lipid Nanoparticle Systems for Systemic Delivery of siRNA”
Session II: Jeff Leyton, PhD (Postdoctoral Fellow, Raymond Reilly Lab, UofT), “Targeting CD123-Positive Leukemia Stem Cells – Pharmacokinetic Lessons Learned from Molecular Imaging Approaches”
Coffee Break – 3:15pm to 3:30pm
Symposium 4 – 3:30pm to 5:45pm - Clinical trials/important issues, road blocks, experiences etc.
Session I: Marko Skrtic (MD/PhD Student, Aaron Schimmer Lab, PMH/OCI ), “Inhibition of Mitochondrial translation as a Novel therapeutic Strategy for AML - From Bench to Bedside”
Session II: Dr. David Kirn (Jennerex Biotherapeutics), "Targeted and Transgene-armed Oncoloytic Vaccinia Viruses for Cancer"
Session III: Dr. Ronan Foley (Juravinski Cancer Centre), “ Bench to Clinic - ‘The Long and Winding Road’”