Attisano and Wrana Labs

SUMMARY OF OUR RESEARCH

The overall focus of our research labs is to understand how networks of interconnected signalling pathways control developmental and homeostatic processes and how disruption of their activities contributes to disease. For this, our research efforts have been directed towards two morphogen signalling pathways, TGFβ and Wnt. We employ a variety of experimental approaches ranging from molecular, biochemical and cell biology, to robotics-based high-throughput approaches and computational methods. For further information about current research see our Research Overview and Publications pages.

Narimatsu, M., et al. Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell 137, 295-307 (2009).

Silverstri, C., et. al. Genome-wide identification of Smad/Foxh1 targets reveals a role for Fox1 in retinoic acid regulation and forebrain development. Developmental Cell, 14, 411-423 (2008).


ATTISANO & WRANA LABS


SUMMARY OF OUR RESEARCH The overall focus of our research labs is to understand how networks of interconnected signalling pathways control developmental and homeostatic processes and how disruption of their activities contributes to disease. For this, our research efforts have been directed towards two morphogen signalling pathways, TGFβ and Wnt. We employ a variety of experimental approaches ranging from molecular, biochemical and cell biology, to robotics-based high-throughput approaches and computational methods. For further information about current research see our Research Overview and Publications pages. Narimatsu, M., et al. Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell 137, 295-307 (2009). Silverstri, C., et. al. Genome-wide identification of Smad/Foxh1 targets reveals a role for Fox1 in retinoic acid regulation and forebrain development. Developmental Cell, 14, 411-423 (2008).

Last updated January 13, 2011